Job Description
Medical Director, Global Medical Affairs
Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture - one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion - because our differences shape how we hire, collaborate, and innovate. Our team's proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific - it's deeply personal, grounded in the meaningful connections we have built. To learn more, visit and follow Agios on LinkedIn and X.
The impact you will make: Agios Pharmaceuticals is searching for a dynamic
Medical Director to join our purpose-driven Global Medical Affairs team. We want someone who cares about this important work, and who's driven to connect to our mission of helping the patient communities we serve. The
Medical Director, Global Medical Affairs serves as a scientific/medical expert responsible for translating complex data into actionable insights that inform both internal decision-making and external engagement. As a key cross-functional partner, the Medical Director collaborates closely with Commercial, Clinical Development, Regulatory, and Market Access teams, among others, to shape brand and portfolio strategy, integrating real-world evidence and external expert perspectives. The position also plays a critical role in building and maintaining relationships with KOLs and representing the organization in external scientific forums. Additionally, the role oversees medical governance for Ex-US partners, ensuring alignment, compliance, and high-quality execution across global collaborations. Through insight generation and medical leadership and guidance for Ex-US partners, this individual will fulfill a key strategic role driving evidence-based decision-making and advancing the overall medical and scientific impact of the organization globally.
What you will do: - Serve as a medical voice, translating complex scientific data into clear, actionable insights for internal and external stakeholders
- Provide strategic oversight of medical plans, including publications, scientific communications, field medical strategy, and evidence generation
- Ensure all Medical Affairs activities are compliant with regulatory requirements and grounded in scientific integrity
- Act as a key partner to Commercial, Clinical Development, Regulatory, and Market Access teams to ensure cohesive and compliant execution across functions
- Influence brand and portfolio strategy by integrating medical insights, real-world evidence, and external expert perspectives
- Serve as a trusted advisor to executive leadership on medical, scientific, and competitive landscape considerations
- Build and maintain strong relationships with Key Opinion Leaders (KOLs), academic institutions, and professional societies
- Represent the company in external scientific forums, advisory boards, and congresses
- Shape the external scientific narrative and ensure consistency across all stakeholder interactions
- Provide medical oversight and governance for third-party Ex-US commercial partners, ensuring alignment with company strategy, compliance standards, and scientific accuracy
- Establish clear frameworks for engagement with Ex-US external partners, including roles, responsibilities, and decision rights
- Review and approve medical content and initiatives developed by Ex-US partners to ensure accuracy, balance, and adherence to regulatory guidelines
- Monitor Ex-US partner performance and ensure delivery of high-quality, compliant medical and promotional activities
- Serve as the primary medical point of contact for commercial partnerships, resolving escalations and ensuring alignment across stakeholders
- Guide the development of real-world evidence (RWE) and investigator-sponsored research (ISR) strategies to address unmet data needs
- Synthesize insights from field teams, KOL engagements, and data sources to inform strategy and lifecycle management
- Identify gaps in clinical and scientific knowledge and proactively shape evidence generation plans
What you bring: - Advanced degree (M.D., PhD, Pharm D) (desirable areas of experience include Rare Disease or Hematology).
- 8-10 years in industry (biotech/pharma) specifically within Medical Affairs or closely related functions
- Excellent interpersonal and public speaking skills are required for this high visibility position.
- Demonstrated ability to work in a matrix environment with cross-functional teams.
- Demonstrated leadership experience.
- Approximately 10% annual travel (domestic and international) is required for this position.
Concerned that you don't check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other's differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you're excited about this role but your previous experience doesn't align perfectly with the , we still encourage you to apply. You may be just the right candidate for this role or another opening!
Work Location: Location Agnostic: Work location for this role is based on employee's individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above .
What we will give you: - Deliberate Development. Your professional growth as one of our top priorities.
- Flexibility. We're all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you're at your best, we're at our best.
- Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website.
- Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance.
- The current base salary range for this position at the Director level is expected to be between $183,549 and $275,324 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators.
- Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries.
- Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We're continuously looking to improve the inclusivity of our workforce.
- Commitment to community. We're an active participant in the communities that surround us - the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.
Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.
Job Tags
Full time, Temporary work, Remote work, Work from home, Flexible hours, 3 days per week